Michael Ausiello has posted the following answers to questions about the series. Check it out:
Question: My 21st birthday is today and, aside from a good drink, I would like nothing more than some scoop on Grey’s Anatomy. Please tell me that Callie will find out soon about George and Izzie whoring around behind her back?— Lauren
Ausiello: Poor Callie will remain blissfully unaware until around, um, let’s go with May 10. The following week, I believe the smelly brown stuff hits the fan.
Question: Is Isaiah Washington leaving Grey’s Anatomy?— Karen
Ausiello: If he is, ABC is doing a really good job of keeping a lid on it. This much I know for sure: At the end of next Thursday’s episode, Burke starts to have some serious reservations about marrying Cristina. And you’re never going to believe whom he turns to for advice. (Hint: They had a little dust-up at the Golden Globes.)
Question: On Grey’s, will Jane Doe get an actual identity before the end of the season?— Tara
Ausiello: I hear she’s getting an actual hubby in the season finale, so it stands to reason that her identity is part of the package.
Question: It seems that, on Grey’s Anatomy, Mark’s “failure” to go 60 days without sex must mean, dare I say it, that he’s unable to have sex? Am I right?— Melinda
Ausiello: Nope. I suggest you hunt down someone by the name of Christine Frickle for the answer to this brainteaser. She was the only AA reader who figured out what I meant by “failure.” Congratulations, Christine!
I haven’t been paying much attention to the rumors about Isaiah Washington leaving the show. They’ve been around for months now, and until I hear something official, I’m not going to worry about it.
Poor Callie though.

If George leaves the show and not the idiot who called him a Fag, I will probably quit watching. Too bad, because I am someone that feels there is little on TV and this is the 1st to keep me watching in many years. I really dislike the reruns off/on. Why the big breaks?
no one should leave the show because they are all great actors. and Mcsteamy lied to Addison about the 60 days thing because of her and Alex,
I read in an article yesterday that he leaves on the season finale, because he doesnt get appointed for chief. and he doesnt go to his own wedding.
idk if its true but its like in the magazine I read.
[...] posted rumors that Burke has second thoughts about marrying Cristina, so who knows how those uncertainties will play [...]
i really love George and Izzie. I feel that Callie is a tad bit annoying in how she hovers George. Izzie is his best friend and love strts frm there i guess. and she must really love him (George) to recover from Denny’s death and opens her heart to someone else.
i really dont want to accept the Bourke is leaving. him and Cristina were such a major part of what made the show special. i cant imagine how good the show will be without him. despite everything, his character was unlike the others. i just loved the wedding vows.
hi mau…
i am 100% agrre with you…the show would not be the same without dr preston burke…i love all scenes where he(burke) and christina together. they were lovely…remember the scene where burke console christina when she was having breakingdown after the miscarriage.the scene they were on bed together.burke cuddled christina..that single scene i think was the best scene of grey’s anatomy…i love the wedding vow too…it’s so sweeeeeet..i will never stop loving and admiring dr preston burke…i really hope that he’ll be back for season 5…hopefully…
the show would not be the same without dr preston burke
If anyone is the fag its george, he should leave not burke. The show will not be the same, they will have enough changes next season and with burke gone, this will be the start of the show to die, it takes all the people in it to make the show, with a few gone, its going to slowly die…..
please email the wedding vow said in last episode.. its touching & heartwarmth for womens.. i want a copy of it! a souvenir!!. send it to my email. thanks.