Now, I know there’s probably an endless amount of combinations for favorite characters, but let’s try and narrow it down to one in the actual poll. Who can you simply not live without on that show? Feel free to explain your answer in the comments.
If I forgot someone, please let me know!
Vote on the sidebar to the right.

what do you mean callie is leaving where did you here that i need to know.. not that i like her its just i havent been hereing an new about the show
someone in previous comments said something about it..i dk!
Mc Deamy is the hottest on the show. NO question here.
ADDISON!!!!!!!!!
followed closely by mcsteamy and alex!
Denny!!!!!
Callie…Hands-down.
Definitely McDreamy is the best.. i love his smile
and I don’t like callie
i mostt absoulutley love alex karev he is so hot and he speaks his mind and he has a nice side to him
1. addison – my fave. shes fucking sexy as hell & shes a great actress. love her.
2. meredith – shes just excellent. gotta love her. they make her a real person by making her look ‘washed out’ – she was a great pick for an actress.
3. mcdreamy – really needs to wear less clothes. at the start he was hott as but they really gotta make him hott again
4. izzie – shes fucking great she reminds me of me at the moment.
5. christina – great actress this one makes the show great.
ADDISON.
#1 is george
GEORGE IS AWESOME!
#2 is izzie
IZZIE IS LOVEABLE!
#3 is addison
ADDISON SO SWEET
#4 is “the nazi”
MIRANDA IS JUST PERFECT
HOW CAN U CHOOSE THEY ARE ALL AWESOM….I CANT CHOOSE !!!!!
definitely MEREDITH! for those who whine about her personality, i think you should open you eyes. her character is “dark & twisty” not “perfect and unproblematic”. that’s why most of us can relate to her – we all have “dark & twisty” sides in all of us! and for me, this side of hers makes her all the more human, lovable and real
I must say that my favorite cast member is Izzie. After having watched her star in “Knocked Up,” I see her in a completely different light. To me, she no longer seems to be the inadequate, over-caring, and preoccupied intern that she was in most of the first three seasons. In the course of making a high-budget motion piture, her acting skills have definitely improved. Judging by the last shows of season 3 and this season’s premiere, she now seems able to “juggle” the way that the writers have sculpted Izzie’s character with her own vision of Izzie. And in my opinion, she has done a great job!
Definitely, Meredith!
ERICA HAHN & CRISTINA
Defo Addison!
Meredith, hands down. The whole show revolves around her. Without Meredith Grey, there would be no “Grey’s Anatomy”
Okay so i freakin love christina she is an amazing actress!!! She always makes me laugh… then i love the mer der combo i wouldnt watch the show without that whole romance…izzie and george are soooo anoying as a couple yuck so now i dont like them..
Christina – just the things that comes out of her mouth they crack me up
Alex – he is such an ass sometimes but he still cracks me up
Derek/MCsteamy/mcvet – They are SO HOT
Addison/Merideth – they are adulteress bitches lol
George/Izzy – ha ha george falls down the stairs lol
I like Izzie. She’s pretty..hot and yet she’s that smart and determined. I really like her character.
Miranda, the looks she gives the interns and her humor cracks me up. I’m gonna cheat and pick one more Chritina I adore her character also !!
I will always pick Meredith.
She’s funny,gorgeous(well in real life, in the show she’s supposed to be this washed out person),and i think everybody has a dark and twisty side hidden somewhere, and meredith is woman enough to show it..
All those bright and shiny people annoy me,because no matter what you do, you’ll never be completely bright and shiny.
TEAM MEREDITH!
I wouldn’t watch the show anymore if it weren’t for Cristina and Miranda.
I miss Burke. (though I’m totally annoyed with what he did) The show’s just not the same without him.
I used to like Izzie. But now, she just freakin annoys me. She shouldn’t have won in the Emmys… =(
i always think merideth and derek are the
favorite people on the show.actually i love
everybody.
CRISTINA & BURKE ALL THE WAY…..
WHEN IS George OMALLY LEAVING?
MEREDITH AND MCDREAMY!!!!!!!!
THEY ARE THE HOTTEST COUPLE IN WHOLE FUCKIN WORLD
1. McDreamy – I mean come on, look at his name?
2. Meredith – She’s the show.
3. George – He’s so sweet, and lovable and adorable.
4. (This is where I would say Addison, but she left)
5. Christina – She’s hilarious.
6. Izzie – She’s adorable.
7. Bailey – She’s the Nazi.
1. McDreamy – I mean come on, look at his name?
2. Meredith – She’s the show.
3. George – He’s so sweet, and lovable and adorable.
4. (This is where I would say Addison, but she left)
5. Christina – She’s hilarious.
6. Izzie – She’s adorable.
7. Bailey – She’s the Nazi.
And the rest of the cast as well, I couldn’t live without all of them!!!
my favorite is izzie,christina,and meredith………
MY favorite is McDreamy and Meredith.
I also like Bailey.
Definately Katherine Heigl, she is my favourite actress, and she is really pretty. Her character is so nice, and she really cares deep down about her patients, which i love. Love Katherine
Hottest guy is Sloan, however Deny is so good looking to, and prettiest girl is Izzy. love em’